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This finding implies that the intermodule linker plays an essential as a functional switch of central helix, 3ask allows both the reader modules by making extended contacts with 3zsk tandem at H3-R2 and H3-K9.

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3ASK- Y -Mayal
Structure of UHRF1 in complex with histone tail ; Descriptor, E3 ubiquitin-protein ligase UHRF1, Histone H, ZINC ION, (4 entities in total) ; Functional. 3ask: Image gallery including assembly, Pfam SCOP and CATH domains, ligands and environments. Structure of UHRF1 in complex with histone tail. Help. ENTITY. 3ASK_1. E3 ubiquitin-protein ligase UHRF1 - Homo sapiens. CHROMOSOME. NC_ NC_ 5'.